Parenteral Reconstitution, dilution and administration Protocol

Parenteral Reconstitution, dilution and administration Protocol

Parenteral Reconstitution, dilution and administration Protocol
IV reconstitution	Brand Name	ampicillin
	Dosage Form	injectible powder
	Strength	500mg
	Compatible diluent for Reconstitution	sterile water for injection
	Incompatible diluent for Reconstitution	Hartmann’s and D5W
	Vol. Of diluent for reconstitution	For IM: 500mg in 1.8ml of WFI For IV:500 mg with 5ml of WFI
	Displacement Value
	Method of reconstitution	Shake vigorously
	Strength after reconstitution	For IM: 250mg/ml For IV:  100mg/ml
	Stability after Reconstitution at Room temperature	Used immediately For IM and IV :used within 1 hour
	Stability after Reconstitution at Refrigerator
IV Dilution for Infusion	Compatible diluent for Dilution / IV infusion	Normal Saline
	Incompatible diluent for Dilution / IV infusion	D5W and Hartmann’s
	Max & Min strength after dilution
	Stability after Dilution at Room temperature	8 hours
	Stability after Dilution at Refrigerator	12 hours at 2-8 C
Administration	Direct IV bolus administration	Over 3-5 min
	IM administration
	Intermittent / continuous IV infusion	Over 30-60 min
	Adverse drug reactions associated with administration	Stomach upset, diarrhea, vomiting, mild skin rash